The potential space between the RPE microvilli and photoreceptor outer segments is filled with what?

Prepare for the NBEO Ocular Anatomy Posterior Segment and Cranial Nerves Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

The potential space between the RPE microvilli and photoreceptor outer segments is filled with what?

The space between the RPE microvilli and the photoreceptor outer segments is filled by the interphotoreceptor matrix. This specialized extracellular matrix sits in the subretinal space and is secreted by both the RPE and the photoreceptors. It provides a scaffold for diffusion of nutrients and retinoids between the photoreceptors and the RPE, and it contains binding proteins that help shuttle molecules essential for the visual cycle.

Vitreous humor fills the vitreous body behind the retina, not the subretinal space. Aqueous humor fills the anterior segment, including the chamber angles, not the subretinal area. Retinal tissue refers to the neural layers themselves, not the space between RPE and photoreceptors.

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